Cancer Immune Surgery

The world's first new paradigm of "Immune Surgery and Universal Treatment for various solid tumors"

Mechanism of Action

UMPIC: Ultro-Minimum Incision Personalized Intratumoral Chemoimmunotherapy

The remarkable efficacy of sustained-release library therapy is rooted in its profound understanding and clinical realization of the Abscopal Effect.

By initiating a series of sequentially occurring biological events through intratumoral injection of its core compound formulation, UMPIC induces systemic immunity from local killing.

  • Step 1: Induce immunogenic cell death and release tumor antigens
  • Step 2: Enhance the cross-presentation of antigens
  • Step 3: Promote chemotaxis and tumor infiltration of effector T cells
  • Step 4: Cytotoxic T lymphocyte-mediated tumor cell killing
  • Step 5: Form long-lasting immune memory
  • Step 6: Modulate the immunosuppressive microenvironment
Mechanism of Action
Guidelines
Mechanism

Compound Drug Combination Design

Base Layer

Anti-cancer drugs (IOS-1)

Direct intratumoral killing of tumor cells, releasing a large amount of tumor-associated antigens from coagulated tumor tissue to provide "attack targets" for the immune system.

Core Layer

Sustained-release agent

Acts as a "reservoir", maintaining high concentrations locally for 7-20 days, avoiding rapid metabolism and greatly reducing systemic toxic side effects.

Guide Layer

Immune adjuvant

Functions as an "amplifier" and "navigator", modifying released tumor antigens to be recognized by dendritic cells, enhancing the body's specific immune response.